참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Methylparaben | HCID 7456 | — |
| 반응물 | Benzyl Bromide | HCID 7498 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | Methyl 4-(benzyloxy)benzoate | HCID 299810 | 100.1% |
반응 단계
A mixture of methyl 4-hydroxy-benzoate (10.0 g, 0.066 mol) and potassium carbonate (12 g, 0.086 mol), were taken in acetone (50 ml) and heated at 50° C. for 1 hour. To the reaction mixture benzyl bromide (8.2 ml, 0.072 mol) was added. The mixture was heated at 80° C. for 5 hours. The mixture was cooled to room temperature and filtered through sintered funnel, washed with acetone. Solvent was removed to obtain pure 4-benzyloxy-benzoic acid methyl ester as white solid (16 g, 100%).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 특허 번호 | US08859566B2 |
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| 출처 데이터셋 | uspto-grants-2014_10 |
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| ORD ID | ord-5a3d3e03777448dfa5c9178a4ea936f8 |
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| 출처 메모 | uspto-grants-2014_10 |
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