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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 535985생성일: 2026년 10월 23일

Methylparaben → Methyl 4-(benzyloxy)benzoate

https://huagongshe.com/ko/reaction/535985

반응식

참여 물질

역할이름HCID투입량
반응물MethylparabenHCID 7456—
반응물Benzyl BromideHCID 7498—
반응물Potassium CarbonateHCID 11430—
용매AcetoneHCID 180—
생성물Methyl 4-(benzyloxy)benzoateHCID 299810100.1%

반응 조건

온도50 °C

반응 단계

A mixture of methyl 4-hydroxy-benzoate (10.0 g, 0.066 mol) and potassium carbonate (12 g, 0.086 mol), were taken in acetone (50 ml) and heated at 50° C. for 1 hour. To the reaction mixture benzyl bromide (8.2 ml, 0.072 mol) was added. The mixture was heated at 80° C. for 5 hours. The mixture was cooled to room temperature and filtered through sintered funnel, washed with acetone. Solvent was removed to obtain pure 4-benzyloxy-benzoic acid methyl ester as white solid (16 g, 100%).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08859566B2
출처 데이터셋uspto-grants-2014_10
ORD IDord-5a3d3e03777448dfa5c9178a4ea936f8
출처 메모uspto-grants-2014_10