4-(chloromethyl)-1-methyl-1H-pyrazole hydrochloride → HCID 57383223, 화합물

HRID 536192노트

반응식

HRID 536192 반응식
[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][C:9]2[CH:10]=[CH:11][C:12]([CH2:15][O:16][C:17]3[CH:22]=[CH:21][NH:20][C:19](=[O:23])[N:18]=3)=[N:13][CH:14]=2)=[CH:4][C:3]=1[C:24]([F:27])([F:26])[F:25].Cl.Cl[CH2:30][C:31]1[CH:32]=[N:33][N:34]([CH3:36])[CH:35]=1>>[Cl:1][C:2]1[CH:7]=[CH:6][C:5]([O:8][C:9]2[CH:10]=[CH:11][C:12]([CH2:15][O:16][C:17]3[CH:22]=[CH:21][N:20]([CH2:30][C:31]4[CH:32]=[N:33][N:34]([CH3:36])[CH:35]=4)[C:19](=[O:23])[N:18]=3)=[N:13][CH:14]=2)=[CH:4][C:3]=1[C:24]([F:25])([F:26])[F:27]

참가 물질

3

반응물 2

HCID 567737394-(chloromethyl)-1-methyl-1H-pyrazole hydrochlorideHCID 178518419HCID 178518419, 화합물

생성물 1

HCID 57383223HCID 57383223, 화합물

실험 절차

The title compound was prepared by a procedure similar to that described for E1 starting from 4-{[(5-{[4-chloro-3-(trifluoromethyl)phenyl]oxy}-2-pyridinyl)methyl]oxy}-2(1H)-pyrimidinone and 4-(Chloromethyl)-1-methyl-1H-pyrazole hydrochloride. LC-MS (ESI): m/z 492 [M+H]+; 3.79 min (ret time).

후처리

  1. custom3.79 min (ret time)

출처 및 근거

ORD 기록
ord-c2c3f23e7857465c8960f40b31d46a41
출처 데이터셋
uspto-grants-2014_10
특허 번호
US08859573B2

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