HCID 21698362, 화합물 → 1-[(1-Methyl-1H-pyrazol-4-yl)methyl]-4-{[(4-{[3-(trifluoromethyl)phenyl]oxy}-phenyl)methyl]oxy}-2(1H)-pyridinone

HRID 536200노트

반응식

HRID 536200 반응식
[F:1][C:2]([F:26])([F:25])[C:3]1[CH:4]=[C:5]([O:9][C:10]2[CH:15]=[CH:14][C:13]([CH2:16][O:17][C:18]3[CH:23]=[CH:22][NH:21][C:20](=[O:24])[CH:19]=3)=[CH:12][CH:11]=2)[CH:6]=[CH:7][CH:8]=1.Cl[CH2:28][C:29]1[CH:30]=[N:31][N:32]([CH3:34])[CH:33]=1>>[CH3:34][N:32]1[CH:33]=[C:29]([CH2:28][N:21]2[CH:22]=[CH:23][C:18]([O:17][CH2:16][C:13]3[CH:14]=[CH:15][C:10]([O:9][C:5]4[CH:6]=[CH:7][CH:8]=[C:3]([C:2]([F:1])([F:25])[F:26])[CH:4]=4)=[CH:11][CH:12]=3)=[CH:19][C:20]2=[O:24])[CH:30]=[N:31]1

참가 물질

3

반응물 2

HCID 21698362HCID 21698362, 화합물HCID 679601144-{[(4-{[3-(trifluoromethyl)phenyl]oxy}phenyl)methyl]oxy}-2(1H)-pyridinone

생성물 1

HCID 573832641-[(1-Methyl-1H-pyrazol-4-yl)methyl]-4-{[(4-{[3-(trifluoromethyl)phenyl]oxy}-phenyl)methyl]oxy}-2(1H)-pyridinone

실험 절차

The title compound was prepared by a procedure similar to that described for E21 starting from 4-{[(4-{[3-(trifluoromethyl)phenyl]oxy}phenyl)methyl]oxy}-2(1H)-pyridinone and 4-(chloromethyl)-1-methyl-1H-pyrazole. LC-MS (ESI): m/z 456 [M+H]+; 3.40 min (ret time).

후처리

  1. custom3.40 min (ret time)

출처 및 근거

ORD 기록
ord-2098c9c17b4c42fbb6c8d3270a3caccd
출처 데이터셋
uspto-grants-2014_10
특허 번호
US08859573B2

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