Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Iodine → 2-[2-(Diethylamino)ethyl]-6-phenyl-isothiazolo[5,4-d]pyrimidin-3(2H)-one
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Iodine | HCID 807 | — |
| 반응물 | HCID 178418472 | HCID 178418472 | — |
| 생성물 | 2-[2-(Diethylamino)ethyl]-6-phenyl-isothiazolo[5,4-d]pyrimidin-3(2H)-one | HCID 9905503 | 68.5% |
반응 단계
Using the procedure of Example 20, 3.3 g (0.01 mol) of 4-mercapto-2-phenyl-pyrimidine-5-carboxylic acid (2-diethylamino-ethyl)-amide (from Preparation 36) and 2.54 g (0.01 mol) of iodine were reacted to give 2.25 g of the title compound after recrystallization from isopropanol, mp 106°-107° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05620997 |
| 출처 데이터셋 | uspto-grants-1997_04 |
| ORD ID | ord-1d1e11fe5f674c7fb54b5254332ae6fe |
| 출처 메모 | uspto-grants-1997_04 |