Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrochloric Acid → 2-Aminophenol hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrochloric Acid | HCID 313 | — |
| 반응물 | 2-Aminophenol | HCID 5801 | — |
| 반응물 | HCID 19890176 | HCID 19890176 | — |
| 용매 | Methanol | HCID 887 | — |
| 용매 | p-Toluenesulfonate | HCID 85570 | — |
| 생성물 | 2-Aminophenol hydrochloride | HCID 5800 | — |
반응 단계
In the present invention, the starting material 2-hydrazinylphenol may be in tosylate form. The 2-hydrazinylphenol in tosylate form can be prepared by a process comprising the steps of: (a) dissolving 2-aminophenol in methanol and adding hydrochloride gas thereto to obtain 2-aminophenol hydrochloride (HCl); (b) dissolving the 2-aminophenol hydrochloride in ethanol and adding isopentyl nitrite thereto to make a nitramide intermediate; and (c) adding the intermediate to an ethanol solution containing para-toluenesulfonic acid (PTSA or TsOH) and tin chloride (SnCl2), thereby obtaining 2-hydrazinylphenol tosylate.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08865934B2 |
| 출처 데이터셋 | uspto-grants-2014_10 |
| ORD ID | ord-ee621668dccd43c4895e91a335bdd852 |
| 출처 메모 | uspto-grants-2014_10 |