Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 5392생성일: 2026년 10월 23일
cis Ethyl 3-bromo-2-oxo-1-azacyclodecane-10-carboxylate → cis Ethyl 3-acetoxy-2-oxo-1-azacyclodecane-10-carboxylate
https://huagongshe.com/ko/reaction/5392
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | cis Ethyl 3-bromo-2-oxo-1-azacyclodecane-10-carboxylate | HCID 131718120 | — |
| 촉매 | Silver acetate | HCID 11246 | — |
| 용매 | Dimethylformamide | HCID 6228 | — |
| 용매 | Ethyl Acetate | HCID 8857 | — |
| 생성물 | cis Ethyl 3-acetoxy-2-oxo-1-azacyclodecane-10-carboxylate | HCID 131718121 | — |
반응 단계
Cis ethyl 3-bromo-2-oxo-1-azacyclodecane-10-carboxylate (2.96 g, 9.67 mmol) is dissolved in dimethylformamide (30 mL). Silver acetate (6.35 g, 38 mmol) is added, and the reaction is heated to 100° C. for 3 hours. After cooling back to room temperature, the reaction is diluted with ethyl acetate (100 mL), filtered through a pad of silica gel, and the solvent is evaporated to give crude cis ethyl 3-acetoxy-2-oxo-1-azacyclodecane-10-carboxylate.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
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| 특허 번호 | US05244889 |
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| 출처 데이터셋 | uspto-grants-1993_09 |
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| ORD ID | ord-dcb68cc3bff744d997cc097884f62d34 |
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| 출처 메모 | uspto-grants-1993_09 |
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