Potassium Carbonate → 5-bromo-2-[(N,N-dimethylthiocarbamoyl)oxy]benzaldehyde

HRID 53952

반응식

HRID 53952 반응식
[Br:1][C:2]1[CH:9]=[C:6]([CH:7]=[O:8])[C:5]([OH:10])=[CH:4][CH:3]=1.C(=O)([O-])[O-].[K+].[K+].[CH3:17][N:18]([CH3:22])[C:19](Cl)=[S:20]>CC(C)=O>[Br:1][C:2]1[CH:3]=[CH:4][C:5]([O:10][C:19](=[S:20])[N:18]([CH3:22])[CH3:17])=[C:6]([CH:9]=1)[CH:7]=[O:8]

참가 물질

5

반응물 3

HCID 11430Potassium CarbonateHCID 27871Dimethylthiocarbamoyl chlorideHCID 728635-Bromosalicylaldehyde

생성물 1

HCID 212515955-bromo-2-[(N,N-dimethylthiocarbamoyl)oxy]benzaldehyde수율 78.9%

시약·촉매·용매 1

HCID 180Acetone용매

실험 절차

8.13 g of 5-bromosalicylaldehyde was dissolved in 100 ml of acetone, followed by the addition of 6.7 g of anhydrous potassium carbonate. With stirring at room temperature, 5.0 g of N,N-dimethylthiocarbamoyl chloride was added to the above solution, and the stirring was continued for two hours. The resulting reaction solution was poured into ice water, and crystals thus precipitated were collected by filtration, and dried to obtain 9.2 g of 5-bromo-2-[(N,N-dimethylthiocarbamoyl)oxy]benzaldehyde.

후처리

  1. customThe resulting reaction solution
  2. customthus precipitated
  3. filtrationwere collected by filtration
  4. customdried

출처 및 근거

ORD 기록
ord-aa605a4ee8c24f2dab9b671f6dc79aa2
출처 데이터셋
uspto-grants-1997_04
특허 번호
US05620991

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