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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 541588생성일: 2026년 10월 27일

3,5-Dimethylisoxazole-4-carbonyl Chloride → N-[6-Chloro-2,4,8,22-tetraazatetracyclo[14.3.1.1(3,7).1(9,13)]docosa-1(20), 3(22),4,6,9(21),10,12,16,18-nonaen-12-yl]-1-[(3,5-dimethylisoxazol-4-yl)carbonyl]piperidine-4-carboxamide Trifluoroacetate

https://huagongshe.com/reaction/541588

반응식

참여 물질

역할이름HCID투입량
반응물3,5-Dimethylisoxazole-4-carbonyl ChlorideHCID 2736265—
반응물N-[6-Chloro-2,4,8,22-tetraazatetracyclo[14.3.1.1(3,7).1(9,13)]docosa-1(20), 3(22),4,6,9(21),10,12,16,18-nonaen-12-yl]piperidine-4-carboxamide bis(trifluoroacetate)HCID 86636132—
생성물N-[6-Chloro-2,4,8,22-tetraazatetracyclo[14.3.1.1(3,7).1(9,13)]docosa-1(20), 3(22),4,6,9(21),10,12,16,18-nonaen-12-yl]-1-[(3,5-dimethylisoxazol-4-yl)carbonyl]piperidine-4-carboxamide TrifluoroacetateHCID 8663613536%

반응 단계

The desired compound was prepared according to the procedure of Example A20, using N-[6-chloro-2,4,8,22-tetraazatetracyclo[14.3.1.1(3,7).1(9,13)]docosa-1(20),3(22),4,6,9(21),10,12,16,18-nonaen-12-yl]piperidine-4-carboxamide bis(trifluoroacetate) and 3,5-dimethylisoxazole-4-carbonyl chloride as starting materials in 36% yield. LCMS for C30H31ClN7O3 (M+H)+: m/z=572.2.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08871753B2
출처 데이터셋uspto-grants-2014_10
ORD IDord-e1836ed1be7b47febd7f95f5673a42fa
출처 메모uspto-grants-2014_10