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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 541689생성일: 2026년 10월 26일

2-Furancarboxylic acid, 5-methyl- → N-[6-Chloro-2,4,8,18,22-pentaazatetracyclo[14.3.1.1(3,7).1(9,13)]docosa-1(20),3(22),4,6,9(21),10,12,16,18-nonaen-12-yl]-2-[1-(5-methyl-2-furoyl)piperidin-4-yl]acetamide bis(trifluoroacetate)

https://huagongshe.com/reaction/541689

반응식

참여 물질

역할이름HCID투입량
반응물2-Furancarboxylic acid, 5-methyl-HCID 74710—
반응물N-[6-chloro-2,4,8,18,22-pentaazatetracyclo[14.3.1.1(3,7).1(9,13)]docosa-1(20),3(22),4,6,9(21),10,12,16,18-nonaen-12-yl]-2-piperidin-4-ylacetamide bis(trifluoroacetate)HCID 86636208—
생성물N-[6-Chloro-2,4,8,18,22-pentaazatetracyclo[14.3.1.1(3,7).1(9,13)]docosa-1(20),3(22),4,6,9(21),10,12,16,18-nonaen-12-yl]-2-[1-(5-methyl-2-furoyl)piperidin-4-yl]acetamide bis(trifluoroacetate)HCID 8663621046%

반응 단계

The desired compound was prepared according to the procedure of Example A27, using N-[6-chloro-2,4,8,18,22-pentaazatetracyclo[14.3.1.1(3,7).1(9,13)]docosa-1(20),3(22),4,6,9(21),10,12,16,18-nonaen-12-yl]-2-piperidin-4-ylacetamide bis(trifluoroacetate) and 5-methyl-2-furoic acid as starting materials in 46% yield. LCMS for C30H31ClN7O3 (M+H)+: m/z=572.2.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US08871753B2
출처 데이터셋uspto-grants-2014_10
ORD IDord-302ba3de84534b2da1d6aa4971d73465
출처 메모uspto-grants-2014_10