Methyl 3-amino-5-hydroxybenzoate → HCID 57961641, 화합물

HRID 541940노트

반응식

HRID 541940 반응식
Cl[C:2]1[N:7]=[C:6]([NH:8][C:9]2[CH:10]=[C:11]([S:15][CH2:16][CH2:17][OH:18])[CH:12]=[CH:13][CH:14]=2)[C:5]([Cl:19])=[CH:4][N:3]=1.[NH2:20][C:21]1[CH:22]=[C:23]([CH:28]=[C:29]([OH:31])[CH:30]=1)[C:24]([O:26][CH3:27])=[O:25]>>[Cl:19][C:5]1[C:6]([NH:8][C:9]2[CH:14]=[CH:13][CH:12]=[C:11]([S:15][CH2:16][CH2:17][OH:18])[CH:10]=2)=[N:7][C:2]([NH:20][C:21]2[CH:22]=[C:23]([CH:28]=[C:29]([OH:31])[CH:30]=2)[C:24]([O:26][CH3:27])=[O:25])=[N:3][CH:4]=1

참가 물질

3

반응물 2

HCID 12438277Methyl 3-amino-5-hydroxybenzoateHCID 57961676HCID 57961676, 화합물

생성물 1

HCID 57961641HCID 57961641, 화합물수율 99%

실험 절차

The desired compound was prepared according to the procedure of Example D5, step B, using 2-({3-[(2,5-dichloropyrimidin-4-yl)amino]phenyl}thio)ethanol and methyl 3-amino-5-hydroxybenzoate as the starting materials in 99% yield. LCMS for C20H20ClN4O4S (M+H)+: m/z=446.9.

출처 및 근거

ORD 기록
ord-10545eaeff4e473280efa3df8669d41a
출처 데이터셋
uspto-grants-2014_10
특허 번호
US08871753B2

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