Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,3-Thiazole-2-carbonyl chloride → HCID 86636336, 화합물
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,3-Thiazole-2-carbonyl chloride | HCID 2795211 | — |
| 반응물 | 2-azetidin-3-yl-N-[6-chloro-2,4,8,18,22-pentaazatetracyclo[14.3.1.1(3,7).1(9,13)]docosa-1(20),3(22),4,6,9(21),10,12,16,18-nonaen-12-yl]acetamide tris(trifluoroacetate) | HCID 86636333 | — |
| 생성물 | HCID 86636336 | HCID 86636336 | 66% |
반응 단계
The desired compound was prepared according to the procedure of Example D94 using 2-azetidin-3-yl-N-[6-chloro-2,4,8,18,22-pentaazatetracyclo[14.3.1.1(3,7).1(9,13)]docosa-1(20),3(22),4,6,9(21),10,12,16,18-nonaen-12-yl]acetamide tris(trifluoroacetate) and 1,3-thiazole-2-carbonyl chloride as the starting materials in 66% yield. LCMS for C26H24ClN8O2S (M+H)+: m/z=547.2.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US08871753B2 |
| 출처 데이터셋 | uspto-grants-2014_10 |
| ORD ID | ord-05a338ddc08944f68944b0e561a319bc |
| 출처 메모 | uspto-grants-2014_10 |