Acetonitrile → Debrisoquine

HRID 542286노트

반응식

HRID 542286 반응식
[CH2:1]1[C:10]2[C:5](=[CH:6][CH:7]=[CH:8][CH:9]=2)[CH2:4][CH2:3][NH:2]1.N[N:12]=[CH:13]S(O)(=O)=O.C(#[N:20])C>>[CH:7]1[CH:8]=[CH:9][C:10]2[CH2:1][N:2]([C:13]([NH2:12])=[NH:20])[CH2:3][CH2:4][C:5]=2[CH:6]=1

참가 물질

4

반응물 3

HCID 6342AcetonitrileHCID 70461,2,3,4-TetrahydroisoquinolineHCID 3013981Aminoiminomethane-sulphonic acid

생성물 1

HCID 2966Debrisoquine

실험 절차

Tetrahydroisoquinoline (0.013 m) is treated with aminoiminomethanesulfonic acid (0.01 m) at ambient temperature. After completion of the reaction, it is diluted with acetonitrile, cooled and the solid product is collected by filtration.

후처리

  1. customAfter completion of the reaction, it
  2. temperaturecooled
  3. filtrationthe solid product is collected by filtration

출처 및 근거

ORD 기록
ord-0cd5d279cd8c49429e14cc8a53a6b393
출처 데이터셋
uspto-grants-1987_04
특허 번호
US04656291

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