Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ammonia → Ethyl 3-amino-2-phenylpropyl(diethoxymethyl)phosphinate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ammonia | HCID 222 | — |
| 반응물 | Ethyl 3-nitro-2-phenylpropyl(diethoxymethyl)phosphinate | HCID 14362826 | — |
| 반응물 | HCID 178418361 | HCID 178418361 | — |
| 촉매 | Nickel | HCID 935 | — |
| 용매 | Ethanol | HCID 702 | — |
| 생성물 | Ethyl 3-amino-2-phenylpropyl(diethoxymethyl)phosphinate | HCID 14362832 | — |
반응 단계
A solution of 5.7 g of ethyl 3-nitro-2-phenylpropyl(diethoxymethyl)phosphinate in 60 ml of ethanol is added to 50 g of an 8% solution of ammonia in ethanol. To this are added 9 ml of Raney Nickel and the resulting mixture is hydrogenated at 1 bar until the theoretical amount of hydrogen has been taken up. The mixture is then filtered and the filtrate is concentrated under reduced pressure to give ethyl 3-amino-2-phenylpropyl(diethoxymethyl)phosphinate as a viscous oil, 31P=+44.4 ppm (CDCl3).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04656298 |
| 출처 데이터셋 | uspto-grants-1987_04 |
| ORD ID | ord-2fd2ce54650b4344b9506549685b0c86 |
| 출처 메모 | uspto-grants-1987_04 |