Thionyl Chloride → Allyloxycarbonylaminoacetyl chloride

HRID 542363노트

반응식

HRID 542363 반응식
S(Cl)([Cl:3])=O.[CH2:5]([O:8][C:9]([NH:11][CH2:12][C:13]([OH:15])=O)=[O:10])[CH:6]=[CH2:7]>C1(C)C=CC=CC=1>[CH2:5]([O:8][C:9]([NH:11][CH2:12][C:13]([Cl:3])=[O:15])=[O:10])[CH:6]=[CH2:7]

참가 물질

4

반응물 2

HCID 24386Thionyl ChlorideHCID 11964402N-[(allyloxy)carbonyl]glycine

생성물 1

HCID 14588174Allyloxycarbonylaminoacetyl chloride

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

5.7 ml of thionyl chloride are added at 0° to 3.18 g of allyloxycarbonylaminoacetic acid. At the same temperature, the mixture is then stirred under a protective gas for 2 hours. It is then diluted with absolute toluene and concentrated in a rotary evaporator. IR (CH2Cl2): 3435, 1800, 1725 cm-1.

후처리

  1. concentrationconcentrated in a rotary evaporator

출처 및 근거

ORD 기록
ord-21f6f3af9f874a45969ee296760e163c
출처 데이터셋
uspto-grants-1987_04
특허 번호
US04656165

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