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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 542398생성일: 2026년 10월 26일

Water → 2-[(Oxiran-2-yl)methoxy]anthracene-9,10-dione

https://huagongshe.com/reaction/542398

반응식

참여 물질

역할이름HCID투입량
반응물WaterHCID 962—
반응물EpichlorohydrinHCID 7835—
반응물2-HydroxyanthraquinoneHCID 11796—
반응물Sodium hydrideHCID 24758—
용매N-methyl-2-pyrrolidoneHCID 13387—
생성물2-[(Oxiran-2-yl)methoxy]anthracene-9,10-dioneHCID 1342360150.57%

반응 조건

온도0 °C

반응 단계

112.1 g (0.5 mole) of 2-hydroxyanthraquinone are dissolved in 500 ml of N-methylpyrrolidone, and 12 g (0.5 mole) of sodium hydride are added in portions. When the evolution of gas has ended, 46.37 ml (0.5 mole) of epichlorohydrin are added dropwise at 70° C. and stirring is continued at 70° C. for a further 8 hours. 1.5 liters of water are then added, the mixture is filtered and the filter cake is dried in vacuo. After drying, the product is boiled up again in 1 liter of N,N-dimethylformamide with 10 g of active charcoal and filtered hot. The crystals which precipitate on cooling to 0° C. are separated off by filtration and dried under a high vacuum. 69.45 g (50.57% of theory) of 2-anthraquinonyl glycidyl ether are obtained; melting point: 162°-167° C.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US04657842
출처 데이터셋uspto-grants-1987_04
ORD IDord-f1f5d4946bec4e9abeb9250e65294a87
출처 메모uspto-grants-1987_04