참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | Epichlorohydrin | HCID 7835 | — |
| 반응물 | 2-Hydroxyanthraquinone | HCID 11796 | — |
| 반응물 | Sodium hydride | HCID 24758 | — |
| 용매 | N-methyl-2-pyrrolidone | HCID 13387 | — |
| 생성물 | 2-[(Oxiran-2-yl)methoxy]anthracene-9,10-dione | HCID 13423601 | 50.57% |
반응 단계
112.1 g (0.5 mole) of 2-hydroxyanthraquinone are dissolved in 500 ml of N-methylpyrrolidone, and 12 g (0.5 mole) of sodium hydride are added in portions. When the evolution of gas has ended, 46.37 ml (0.5 mole) of epichlorohydrin are added dropwise at 70° C. and stirring is continued at 70° C. for a further 8 hours. 1.5 liters of water are then added, the mixture is filtered and the filter cake is dried in vacuo. After drying, the product is boiled up again in 1 liter of N,N-dimethylformamide with 10 g of active charcoal and filtered hot. The crystals which precipitate on cooling to 0° C. are separated off by filtration and dried under a high vacuum. 69.45 g (50.57% of theory) of 2-anthraquinonyl glycidyl ether are obtained; melting point: 162°-167° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|
| 특허 번호 | US04657842 |
|---|
| 출처 데이터셋 | uspto-grants-1987_04 |
|---|
| ORD ID | ord-f1f5d4946bec4e9abeb9250e65294a87 |
|---|
| 출처 메모 | uspto-grants-1987_04 |
|---|