Ethanol → HCID 21294041, 화합물

HRID 543229노트

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HRID 543229 반응식
[C:1]([C:4]1[CH:17]=[CH:16][C:7]([O:8][CH2:9][CH2:10][CH2:11][CH2:12][C:13]([OH:15])=[O:14])=[C:6]([CH2:18][CH2:19][CH3:20])[C:5]=1[OH:21])(=[O:3])[CH3:2].S(=O)(=O)(O)O.[CH2:27](O)[CH3:28]>>[C:1]([C:4]1[CH:17]=[CH:16][C:7]([O:8][CH2:9][CH2:10][CH2:11][CH2:12][C:13]([O:15][CH2:27][CH3:28])=[O:14])=[C:6]([CH2:18][CH2:19][CH3:20])[C:5]=1[OH:21])(=[O:3])[CH3:2]

참가 물질

4

반응물 3

HCID 702EthanolHCID 1118Sulfuric AcidHCID 13753872HCID 13753872, 화합물

생성물 1

HCID 21294041HCID 21294041, 화합물

실험 절차

Eleven grams of 5-(4-acetyl-3-hydroxy-2-propylphenoxy)pentanoic acid were dissolved in 200 ml. of absolute ethanol. With stirring, 1 ml. of sulfuric acid was added and the reaction was stirred overnight. The solvent was evaporated in vacuo and the residue partitioned between ethyl acetate and dilute potassium carbonate solution. The ethyl acetate was separated, dried, and evaporated to give 9.9 g. of the title product, M+ =322.

후처리

  1. stirringthe reaction was stirred overnight
  2. customThe solvent was evaporated in vacuo
  3. customthe residue partitioned between ethyl acetate and dilute potassium carbonate solution
  4. customThe ethyl acetate was separated
  5. customdried
  6. customevaporated
  7. customto give 9.9 g

출처 및 근거

ORD 기록
ord-4b5c60c903f34129b873a64555b056d7
출처 데이터셋
uspto-grants-1987_04
특허 번호
US04661505

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