Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Water → 2-(2-Iodo-5-methoxyphenyl)acetic acid
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Water | HCID 962 | — |
| 반응물 | (3-Methoxyphenyl)acetic acid | HCID 15719 | — |
| 반응물 | Iodine chloride | HCID 24640 | — |
| 촉매 | Iodine | HCID 807 | — |
| 용매 | Acetic Acid | HCID 176 | — |
| 생성물 | 2-(2-Iodo-5-methoxyphenyl)acetic acid | HCID 820071 | 65% |
반응 단계
A solution of 45 g (0.27 mole) of 3-methoxybenzeneacetic acid, 52.6 g (0.32 mole) of iodine monochloride and 1 g of iodine was allowed to stand in 500 ml of glacial acetic acid for six days at room temperature. The reaction was poured into water and the solid collected. It was recrystallized from toluene to give 51 g of crystalline 2-iodo-5-methoxybenzeneacetic acid, mp 133.5°-134.5° C. (65% yield).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US04661635 |
| 출처 데이터셋 | uspto-grants-1987_04 |
| ORD ID | ord-b4f7f8a97a8e42fb9576438e9b94f03a |
| 출처 메모 | uspto-grants-1987_04 |