Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Acetic Anhydride → n-[4-Chloro-3-(trifluoromethyl)phenyl]acetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Acetic Anhydride | HCID 7918 | — |
| 반응물 | 4-Chloro-3-(trifluoromethyl)aniline | HCID 67574 | — |
| 생성물 | n-[4-Chloro-3-(trifluoromethyl)phenyl]acetamide | HCID 67676 | 98.5% |
반응 단계
A solution of 3-amino-6-chlorobenzotrifluoride (1.045 g, 5.34 mmol, Aldrich) in acetic anhydride (5 mL) was stirred at room temperature for 12 h to produce a white needle precipitate. It was filtered to give 1.250 g (98.5%) of 3-acetamido-6-chlorobenzotrifluoride. 1H NMR (CDCl3): δ2.193 (s, 3H); 7.420 (d, 1H, J=8.7 Hz); 7.726 (m, 2H), 7.804 (s, 1H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05622952 |
| 출처 데이터셋 | uspto-grants-1997_04 |
| ORD ID | ord-1e1bfe82ffb14a0295567788d10cbeb5 |
| 출처 메모 | uspto-grants-1997_04 |