N-[4-Chloro-2-nitro-5-(trifluoromethyl)phenyl]acetamide → 4-Chloro-2-nitro-5-(trifluoromethyl)aniline

참여 물질

반응 단계

A mixture of 3-acetamido-6-chloro-4-nitrobenzotrifluoride (780 mg, 2.76 mmol) in concentrated HCl (3 mL) was refluxed overnight and it was extracted by ethyl acetate (2×3 mL). The extract was dried over Mg2SO4 and evaporated to give 517 mg (78%) of 3-amino-6-chloro-4-nitrobenzotrifluoride. 1H NMR (CDCl3): δ6.205 (s, 2H); 7.206 (s, 1H); 8.263 (s, 1H).

출처 및 근거