Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-[2-(Methylsulfonylamino)ethylthio]imidazo[1,2-a]pyridine → 5-[2-(Methylsulfonylamino)ethylthio]imidazo[1,2-a]pyridine.hydrochloride
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-[2-(Methylsulfonylamino)ethylthio]imidazo[1,2-a]pyridine | HCID 15229363 | — |
| 반응물 | Hydrochloride methanol | HCID 21893726 | — |
| 용매 | Methanol | HCID 887 | — |
| 생성물 | 5-[2-(Methylsulfonylamino)ethylthio]imidazo[1,2-a]pyridine.hydrochloride | HCID 20086655 | 89.3% |
반응 단계
A suspension of 5-[2-(methylsulfonylamino)ethylthio]imidazo[1,2-a]pyridine (543 g, 2 mmoles) in methanol (20 ml) was treated with hydrogen chloride-methanol. After the solvent was distilled off, the residue was crystallized from chloroform ether. Then, the crystals thus obtained were washed with ether and dried to obtain 550 mg of the desired product (89.3%, colorless crystals).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05244908 |
| 출처 데이터셋 | uspto-grants-1993_09 |
| ORD ID | ord-90e3544a7e8d48009be88fd306d4e8e7 |
| 출처 메모 | uspto-grants-1993_09 |