1-Propanol → Propyl 4-[7-(3-methylisoxazol-5-yl)heptoxy]benzoate

HRID 544612노트

반응식

HRID 544612 반응식
[C:1]([C:4]1[CH:23]=[CH:22][C:7]([O:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][C:16]2[O:20][N:19]=[C:18]([CH3:21])[CH:17]=2)=[CH:6][CH:5]=1)([OH:3])=[O:2].[CH2:24](O)[CH2:25][CH3:26]>>[CH2:24]([O:2][C:1]([C:4]1[CH:5]=[CH:6][C:7]([O:8][CH2:9][CH2:10][CH2:11][CH2:12][CH2:13][CH2:14][CH2:15][C:16]2[O:20][N:19]=[C:18]([CH3:21])[CH:17]=2)=[CH:22][CH:23]=1)=[O:3])[CH2:25][CH3:26]

참가 물질

3

반응물 2

HCID 10311-PropanolHCID 52712095-[7-(4-Carboxyphenoxy)heptyl]-3-methylisoxazole

생성물 1

HCID 5271195Propyl 4-[7-(3-methylisoxazol-5-yl)heptoxy]benzoate

실험 절차

[I; R is CH3, n is 7, X is O, Ar is 4--CH3 (CH2)2OOCC6H4 ], m.p. 54° C., from 5-[7-(4-carboxyphenoxy)heptyl]-3-methylisoxazole (Example 16) and n-propyl alcohol; MIC vs. rhinovirus Type 2 in vitro=0.07 μg/ml.

출처 및 근거

ORD 기록
ord-af0fc335aa43428c9909e138d434cb69
출처 데이터셋
uspto-grants-1984_05
특허 번호
US04451476

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