Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Benzyl Bromide → 1-Benzyl-N-tert-butylcyclopropane-1-sulfonamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Benzyl Bromide | HCID 7498 | — |
| 반응물 | Ethyl Acetate | HCID 8857 | — |
| 반응물 | N-tert-butyl-1-methylcyclopropane-1-sulfonamide | HCID 21889792 | — |
| 용매 | Hexane | HCID 8058 | — |
| 생성물 | 1-Benzyl-N-tert-butylcyclopropane-1-sulfonamide | HCID 21889796 | 60% |
반응 단계
This compound was obtained in 60% yield using the procedure described for the synthesis of N-tert-butyl-(1-methyl)cyclopropylsulfonamide using 1.05 equivalents of benzyl bromide. Trituration with 10% ethyl acetate in hexane provided the desired product: 1H NMR (CDCl3) δ 0.92 (m, 2H), 1.36 (m, 2H), 1.43 (s, 9H), 3.25 (s, 2H), 4.62 (br s, 1H), 7.29-7.36 (m, 5H).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07935670B2 |
| 출처 데이터셋 | uspto-grants-2011_05 |
| ORD ID | ord-6d20e2ce2296407ca15246884a172a42 |
| 출처 메모 | uspto-grants-2011_05 |