Ethyl bromopyruvate → HCID 178470113, 화합물

HRID 545105

반응식

HRID 545105 반응식
Br[CH2:2][C:3](=O)[C:4]([O:6][CH2:7][CH3:8])=[O:5].[C:10](=[S:13])([S-:12])[NH2:11].[NH4+]>C(O)C>[CH2:7]([O:6][C:4]([C:3]1[N:11]=[C:10]([SH:13])[S:12][CH:2]=1)=[O:5])[CH3:8]

참가 물질

4

반응물 2

HCID 66144Ethyl bromopyruvateHCID 11083854Ammonium dithiocarbamate

생성물 1

HCID 178470113HCID 178470113, 화합물수율 65.9%

시약·촉매·용매 1

HCID 702Ethanol용매

실험 절차

Ethyl bromopyruvate (90%, 100 g) was completely dissolved in ethanol (1000 mL), ammonium dithiocarbamate (55.9 g) was added, and the mixture was stirred at room temperature for 2.5 hrs and heated under reflux for 1 hr. After completion of the reaction, the solvent was evaporated under reduced pressure, water was added to the obtained residue. The solid was collected by filtration, washed with water and isopropyl ether, and dried to give the title compound (63.3 g) as a yellow powder.

후처리

  1. temperatureheated
  2. temperatureunder reflux for 1 hr
  3. customAfter completion of the reaction
  4. customthe solvent was evaporated under reduced pressure, water
  5. additionwas added to the obtained residue
  6. filtrationThe solid was collected by filtration
  7. washwashed with water and isopropyl ether
  8. customdried

출처 및 근거

ORD 기록
ord-e1e5dc99a7c84d74bd109e9411a8dee4
출처 데이터셋
uspto-grants-2011_05
특허 번호
US07935700B2

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