Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
4-Chloro-3-(trifluoromethyl)benzaldehyde → (2S)-N-{[4-(4-chlorobenzyl)morpholin-2-yl]methyl}-[4-(ethoxycarbonylmethyl)thiazol-2-ylthio]acetamide
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 4-Chloro-3-(trifluoromethyl)benzaldehyde | HCID 118642 | — |
| 반응물 | (2S)-[4-(ethoxycarbonylmethyl)thiazol-2-ylthio]-N-[(morpholin-2-yl)methyl]acetamide | HCID 67169399 | — |
| 생성물 | (2S)-N-{[4-(4-chlorobenzyl)morpholin-2-yl]methyl}-[4-(ethoxycarbonylmethyl)thiazol-2-ylthio]acetamide | HCID 67168675 | — |
| 생성물 | (2S)-N-{[4-(4-chloro-3-trifluoromethylbenzyl)morpholin-2-yl]methyl}-[4-(ethoxycarbonylmethyl)thiazol-2-ylthio]acetamide | HCID 67168871 | — |
반응 단계
By a similar method as in (85-1), the title compound (663 mg) was obtained as a colorless oil from the resultant product (899 mg) of (75-3) and 4-chloro-3-trifluoromethylbenzaldehyde (396 μL).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07935700B2 |
| 출처 데이터셋 | uspto-grants-2011_05 |
| ORD ID | ord-27bf704376c34903820ed2eb95adfcb7 |
| 출처 메모 | uspto-grants-2011_05 |