1-Azido-1-(5-chloro-2-pyridyl)-2-(1H-imidazol-1-yl)ethane → 1-Amino-1-(5-chloro-2-pyridyl)-2-(1H-imidazol-1-yl)ethane

HRID 54516

반응식

HRID 54516 반응식
[N:1]([CH:4]([C:11]1[CH:16]=[CH:15][C:14]([Cl:17])=[CH:13][N:12]=1)[CH2:5][N:6]1[CH:10]=[CH:9][N:8]=[CH:7]1)=[N+]=[N-]>N1C=CC=CC=1>[NH2:1][CH:4]([C:11]1[CH:16]=[CH:15][C:14]([Cl:17])=[CH:13][N:12]=1)[CH2:5][N:6]1[CH:10]=[CH:9][N:8]=[CH:7]1

참가 물질

3

반응물 1

HCID 199594151-Azido-1-(5-chloro-2-pyridyl)-2-(1H-imidazol-1-yl)ethane

생성물 1

HCID 199594121-Amino-1-(5-chloro-2-pyridyl)-2-(1H-imidazol-1-yl)ethane

시약·촉매·용매 1

HCID 1049Pyridine용매

실험 절차

A solution of 0.83 g of 1-azido-1-(5-chloro-2-pyridyl)-2-(1H-imidazol-1-yl)ethane in 4 ml of dry pyridine is stirred under a H2S-atmosphere for 3 hours. The reaction mixture is evaporated, the residue is redissolved in 5 ml of dilute acetic acid (acetic acid/water 1/4) and extracted with ethyl acetate. The combined organic phases are evaporated to give the title product as a yellowish oil.

후처리

  1. customThe reaction mixture is evaporated
  2. dissolutionthe residue is redissolved in 5 ml of dilute acetic acid (acetic acid/water 1/4)
  3. extractionextracted with ethyl acetate
  4. customThe combined organic phases are evaporated

출처 및 근거

ORD 기록
ord-6fca47c8e7d641399db54b7af3e220ea
출처 데이터셋
uspto-grants-1997_04
특허 번호
US05622982

연결된 노트

불러오는 중…