Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
2-Nitrophenol → Benzyl 2-nitrophenyl ether
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 2-Nitrophenol | HCID 6947 | — |
| 반응물 | Benzyl Bromide | HCID 7498 | — |
| 반응물 | Potassium Carbonate | HCID 11430 | — |
| 용매 | Acetone | HCID 180 | — |
| 생성물 | Benzyl 2-nitrophenyl ether | HCID 736266 | — |
반응 단계
A stirred mixture of 2-nitrophenol (13.9 g, 0.10 mol), benzyl bromide (12.0 ml, 0.10 mol) and anhydrous potassium carbonate (30 g, 0.22 mol) in acetone (200 ml) is heated under reflux for 16 hours, cooled, poured onto ice-dilute hydrochloric acid, and extracted with dichloromethane. The extract is dried and evaporated and the residue is crystallized from ether-hexane as pale crystals, m.p. <50° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05622969 |
| 출처 데이터셋 | uspto-grants-1997_04 |
| ORD ID | ord-e44dbfde469446e78ff3839f598915a5 |
| 출처 메모 | uspto-grants-1997_04 |