Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Cornforth reagent → Indole-7-carboxaldehyde
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Cornforth reagent | HCID 2724130 | — |
| 반응물 | (1H-indol-7-yl)methanol | HCID 2773460 | — |
| 용매 | Dichloromethane | HCID 6344 | — |
| 생성물 | Indole-7-carboxaldehyde | HCID 2734629 | — |
반응 단계
Solid pyridinium dichromate (1.77 g, 5.1 mmol) is added in portions over 3 hours to a stirred solution of 7-indolemethanol (0.5 g, 3.4 mmol) in dichloromethane (50 ml). The mixture is stirred for a further 2 hours then filtered through a pad of Celite filter aid. The filtrate is evaporated and the residue purified by chromatography on silica in ethyl acetate-hexane (1:3)
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05622969 |
| 출처 데이터셋 | uspto-grants-1997_04 |
| ORD ID | ord-4cd06d0fdd3140dc9e0b2b96b9a110a2 |
| 출처 메모 | uspto-grants-1997_04 |