Ammonium trifluoroacetate → HCID 67132990, 화합물

반응식

[CH2:1]([O:3][C:4](=[O:37])[CH:5]([N:20]([CH:34]1[CH2:36][CH2:35]1)[C:21](=O)[C:22]1[CH:27]=[CH:26][C:25]([O:28][C:29]([F:32])([F:31])[F:30])=[CH:24][CH:23]=1)[C:6]([C:8]1[N:9]=[N:10][N:11]([CH2:13][C:14]2[CH:19]=[CH:18][CH:17]=[CH:16][CH:15]=2)[CH:12]=1)=O)[CH3:2].FC(F)(F)C([O-])=O.[NH4+:45]>>[CH2:1]([O:3][C:4]([C:5]1[N:20]([CH:34]2[CH2:35][CH2:36]2)[C:21]([C:22]2[CH:27]=[CH:26][C:25]([O:28][C:29]([F:30])([F:31])[F:32])=[CH:24][CH:23]=2)=[N:45][C:6]=1[C:8]1[N:9]=[N:10][N:11]([CH2:13][C:14]2[CH:15]=[CH:16][CH:17]=[CH:18][CH:19]=2)[CH:12]=1)=[O:37])[CH3:2]

참가 물질

반응물 2

HCID 2724268Ammonium trifluoroacetate

HCID 67133208HCID 67133208, 화합물

생성물 1

HCID 67132990HCID 67132990, 화합물

실험 절차

The title compound was prepared from 3-(1-benzyl-1H-[1,2,3]triazol-4-yl)-2-[cyclopropyl-(4-trifluoromethoxy-benzoyl)-amino]-3-oxo-propionic acid ethyl ester in direct analogy to intermediate 8B, by reaction with ammonium trifluoroacetate. MS: 498.1 (MH+).

출처 및 근거

ORD 기록: ord-b1ca4310590448979ea00c9548f7cee7
출처 데이터셋: uspto-grants-2011_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07935707B2

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