Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
1,4'-Bipiperidin-4-ol → (4-Hydroxy-[1,4']bipiperidinyl-1'-yl)-[5-iodo-3-methyl-2-(3-trifluoromethyl-phenyl)-3H-imidazol-4-yl]-methanone
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 1,4'-Bipiperidin-4-ol | HCID 22061342 | — |
| 반응물 | 5-iodo-3-methyl-2-(3-trifluoromethyl-phenyl)-3H-imidazole-4-carboxylic acid | HCID 67133231 | — |
| 생성물 | (4-Hydroxy-[1,4']bipiperidinyl-1'-yl)-[5-iodo-3-methyl-2-(3-trifluoromethyl-phenyl)-3H-imidazol-4-yl]-methanone | HCID 57541095 | — |
반응 단계
In analogy to the procedure described for example 2, 5-iodo-3-methyl-2-(3-trifluoromethyl-phenyl)-3H-imidazole-4-carboxylic acid (example 36) was coupled with [1,4′]bipiperidinyl-4-ol to give the title compound as light red solid. MS: 563.2 (MH+).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07935707B2 |
| 출처 데이터셋 | uspto-grants-2011_05 |
| ORD ID | ord-f659f54d5b384fa598484b831946b276 |
| 출처 메모 | uspto-grants-2011_05 |