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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 545416생성일: 2026년 10월 27일

[1,4'-Bipiperidin]-3-ol → (Rac)-(3-hydroxy-[1,4']bipiperidinyl-1'-yl)-[5-iodo-3-methyl-2-(3-trifluoromethyl-phenyl)-3h-imidazol-4-yl]-methanone

https://huagongshe.com/reaction/545416

반응식

참여 물질

역할이름HCID투입량
반응물[1,4'-Bipiperidin]-3-olHCID 21091574—
반응물5-iodo-3-methyl-2-(3-trifluoromethyl-phenyl)-3H-imidazole-4-carboxylic acidHCID 67133231—
생성물(Rac)-(3-hydroxy-[1,4']bipiperidinyl-1'-yl)-[5-iodo-3-methyl-2-(3-trifluoromethyl-phenyl)-3h-imidazol-4-yl]-methanoneHCID 57541103—

반응 단계

In analogy to the procedure described for example 2, 5-iodo-3-methyl-2-(3-trifluoromethyl-phenyl)-3H-imidazole-4-carboxylic acid (example 36) was coupled with (rac)-[1,4′]bipiperidinyl-3-ol to give the title compound as off-white solid. MS: 563.2 (MH+).

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07935707B2
출처 데이터셋uspto-grants-2011_05
ORD IDord-54834fbcda474a9380af99baa2752d52
출처 메모uspto-grants-2011_05