Trimethylsilyldiazomethane → 2-Acetamidoacrylic acid

HRID 546326

반응식

HRID 546326 반응식
C[O:2][C:3](=[O:10])[C@@H:4]([NH:6][C:7](=[O:9])[CH3:8])[CH3:5].[Si](C=[N+]=[N-])(C)(C)C>>[C:7]([NH:6][C:4](=[CH2:5])[C:3]([OH:10])=[O:2])(=[O:9])[CH3:8]

참가 물질

3

반응물 2

HCID 167693TrimethylsilyldiazomethaneHCID 6951030(S)-Methyl 2-acetamidopropanoate

생성물 1

HCID 794822-Acetamidoacrylic acid

실험 절차

(S)-2-Acetylaminopropionic acid methyl ester, conversion>99%, ee>99% (derivatised using TMS-diazomethane and then analysed using the same method developed for the methyl ester).

출처 및 근거

ORD 기록
ord-099ac82866b340beb0efcec807ffb5ee
출처 데이터셋
uspto-grants-2011_05
특허 번호
US07935841B2

연결된 노트

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