Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
6,7-Dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline → 3,4-Dihydro-6,7-dimethoxy-1-methylisoquinoline
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 6,7-Dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline | HCID 10302 | — |
| 반응물 | Acetic anhydride pyridine | HCID 22348678 | — |
| 생성물 | 3,4-Dihydro-6,7-dimethoxy-1-methylisoquinoline | HCID 22652 | — |
반응 단계
6,7-Dimethoxy-1-methyl-1,2,3,4-tetrahydroisoquinoline, conversion>99%, ee 82% (GC, sample derivatised by treatment with acetic anhydride pyridine, Chirasil DEX CB, 25 m×0.25 mm, injector/detector 200° C., helium 20 psi, 170° C. for 20 minutes then ramp at 5° C./min to 200° C., hold for 10 minutes, retention times 30.18 minutes and 30.45 minutes).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07935841B2 |
| 출처 데이터셋 | uspto-grants-2011_05 |
| ORD ID | ord-c4b619383e4c49889daed010d1c31a9b |
| 출처 메모 | uspto-grants-2011_05 |