Phosgene → 4-(Chloromethyl)-2,5-oxazolidinedione

HRID 54777노트

반응식

HRID 54777 반응식
Cl[C@@:2]([C:5]([OH:7])=[O:6])([CH3:4])[NH2:3].C(Cl)([Cl:10])=O.[O:12]1[CH2:16]CCC1>C1(C)C=CC=CC=1>[Cl:10][CH2:4][CH:2]1[C:5](=[O:6])[O:7][C:16](=[O:12])[NH:3]1

참가 물질

5

반응물 3

HCID 6371PhosgeneHCID 8028TetrahydrofuranHCID 45086566HCID 45086566, 화합물

생성물 1

HCID 217642954-(Chloromethyl)-2,5-oxazolidinedione

시약·촉매·용매 1

HCID 1140Toluene용매

실험 절차

The title compound is prepared by the procedure of Example 50 using 1.24 g of 2-chloro-L-alanine, 16 ml of 1.93M phosgene in toluene and 55 ml of tetrahydrofuran to give 0.150 g of the desired product.

출처 및 근거

ORD 기록
ord-feb24f8b00244efcad0c82f5b39c2f44
출처 데이터셋
uspto-grants-1997_04
특허 번호
US05623081

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