1-(4-methoxyphenyl)-N-methylmethanamine → 4-(N-(4-methoxybenzyl)-N-methylsulfamoyl)benzoic acid

HRID 548061

반응식

HRID 548061 반응식
[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][NH:10][CH3:11])=[CH:5][CH:4]=1.Cl[S:13]([C:16]1[CH:25]=[CH:24][C:19]([C:20]([O:22]C)=[O:21])=[CH:18][CH:17]=1)(=[O:15])=[O:14]>>[CH3:1][O:2][C:3]1[CH:8]=[CH:7][C:6]([CH2:9][N:10]([CH3:11])[S:13]([C:16]2[CH:17]=[CH:18][C:19]([C:20]([OH:22])=[O:21])=[CH:24][CH:25]=2)(=[O:15])=[O:14])=[CH:5][CH:4]=1

참가 물질

3

반응물 2

HCID 4854071-(4-methoxyphenyl)-N-methylmethanamineHCID 4738388Methyl 4-(Chlorosulfonyl)benzoate

생성물 1

HCID 252076194-(N-(4-methoxybenzyl)-N-methylsulfamoyl)benzoic acid

실험 절차

Prepared as in example 5-27 from 1-(4-methoxyphenyl)-N-methylmethanamine and methyl 4-(chlorosulfonyl)-benzoate (Example 5-10c). MS (M−H, 335.1); 1H NMR (400 MHz, DMSO-d6): δ, ppm: 2.51 (s, 3H), 3.71 (s, 3H), 4.05 (s, 2H), 6.88 (d, 2H), 7.18 (d, 2H), 7.91 (d, 2H); 8.13 (d, 2H). Elemental analysis: (found): C, 57.47%; H, 4.77%; and N, 4.31%. (theoretical): C, 57.30%; H, 5.11%; and N, 4.18%.

출처 및 근거

ORD 기록
ord-38fd8da1109b4abca86166f867ab23ea
출처 데이터셋
uspto-grants-2011_05
특허 번호
US07939671B2

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