Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
5-[2-(Amino)ethylthio]imidazo[1,2-a]pyridine dihydrochloride → 5-[2-(Amino)ethylthio]imidazo[1,2-a]pyridine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | 5-[2-(Amino)ethylthio]imidazo[1,2-a]pyridine dihydrochloride | HCID 23362833 | — |
| 용매 | Chloroform | HCID 6212 | — |
| 생성물 | 5-[2-(Amino)ethylthio]imidazo[1,2-a]pyridine | HCID 15229369 | 99.7% |
반응 단계
After a suspension of 5-[2-(amino)ethylthio]imidazo-[1,2-a]pyridine dihydrochloride (13.31 g, 50 mmloes) in chloroform (200 ml) was washed with 3N sodium hydroxide (50 ml), the aqueous layer was extracted with chloroform, the combined chloroform layer was dried over anhydrous magnesium sulfate. Then, the solvent was distilled off to obtain 9.63 g of the desired product (99.7%, pale yellow oily product).
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05244908 |
| 출처 데이터셋 | uspto-grants-1993_09 |
| ORD ID | ord-d247e64e0eef42c0ae0a6b34795adbf6 |
| 출처 메모 | uspto-grants-1993_09 |