Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Ethylene Glycol → 1,4-Dioxa-8-thiaspiro(4.5)decane
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Ethylene Glycol | HCID 174 | — |
| 반응물 | Benzene | HCID 241 | — |
| 반응물 | p-Toluenesulfonic acid | HCID 6101 | — |
| 반응물 | Tetrahydrothiopyran-4-one | HCID 66173 | — |
| 용매 | Water | HCID 962 | — |
| 생성물 | 1,4-Dioxa-8-thiaspiro(4.5)decane | HCID 12335978 | — |
반응 단계
A mixture of 5.0 g of tetrahydrothiopyran-4-one, 2.5 ml of ethylene glycol, 0.230 g of p-toluenesulfonic acid and 125 ml of benzene is stirred at reflux temperature for 2.5 hours. The water formed is removed using a Dean-Stark trap. The reaction is treated with saturated sodium bicarbonate, water, saturated sodium chloride, dried and concentrated in vacuo to give 6.52 g of the desired product as an oil.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05623081 |
| 출처 데이터셋 | uspto-grants-1997_04 |
| ORD ID | ord-3e940006c8d94ab8a3f705c659dcaa0b |
| 출처 메모 | uspto-grants-1997_04 |