1,3-dimethyl-4,5,6,7-tetrahydro-1H-indene → Lithium 1,3-dimethyl-4,5,6,7-tetrahydro-1H-inden-1-ide

HRID 54888노트

반응식

HRID 54888 반응식
[CH3:1][C:2]1[C:3]2[CH2:4][CH2:5][CH2:6][CH2:7][C:8]=2[CH:9]([CH3:11])[CH:10]=1.[Li:12]CCCC>CCCCC>[CH3:1][C-:2]1[C:3]2[CH2:4][CH2:5][CH2:6][CH2:7][C:8]=2[C:9]([CH3:11])=[CH:10]1.[Li+:12]

참가 물질

4

반응물 2

HCID 129801691,3-dimethyl-4,5,6,7-tetrahydro-1H-indeneHCID 178418339Butyllithium

생성물 1

HCID 23721395Lithium 1,3-dimethyl-4,5,6,7-tetrahydro-1H-inden-1-ide수율 97%

시약·촉매·용매 1

HCID 8003Pentane용매

실험 절차

7,9 dimethylbicyclo-[4.3.0]-nona-1(6),7-diene (5.0 g, 33.5 mmol) was added to 100 mL of pentane. To this solution nBuLi (2.7M, 13 mL) was added dropwise, and the mixture was stirred for 12 hours. The resulting white precipitate was collected via filtration, washed with pentane and dried under reduced pressure to give 5.02 g (97 percent) of product.

후처리

  1. filtrationThe resulting white precipitate was collected via filtration
  2. washwashed with pentane
  3. customdried under reduced pressure

출처 및 근거

ORD 기록
ord-45ccc4ad28a94c87b29225a17b7cd435
출처 데이터셋
uspto-grants-1997_04
특허 번호
US05624878

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