2-Bromo-1-(4-fluorophenyl)ethan-1-one → HCID 86629008, 화합물

HRID 549337

반응식

HRID 549337 반응식
[C:1]([O:5][C:6]([N:8]1[CH2:12][CH2:11][CH2:10][C@H:9]1[CH2:13][C:14]([OH:16])=[O:15])=[O:7])([CH3:4])([CH3:3])[CH3:2].Br[CH2:18][C:19]([C:21]1[CH:26]=[CH:25][C:24]([F:27])=[CH:23][CH:22]=1)=[O:20]>>[C:1]([O:5][C:6]([N:8]1[CH2:12][CH2:11][CH2:10][C@H:9]1[CH2:13][C:14]([O:16][CH2:18][C:19]([C:21]1[CH:26]=[CH:25][C:24]([F:27])=[CH:23][CH:22]=1)=[O:20])=[O:15])=[O:7])([CH3:4])([CH3:2])[CH3:3]

참가 물질

3

반응물 2

HCID 967492-Bromo-1-(4-fluorophenyl)ethan-1-oneHCID 688605(S)-2-(1-BOC-2-pyrrolidinyl)acetic acid

생성물 1

HCID 86629008HCID 86629008, 화합물수율 99.5%

실험 절차

The title compound (3.2 g) was prepared from (S)-2-carboxymethyl-pyrrolidine-1-carboxylic acid tert butyl ester (2.02 g) and 2-bromo-4′-fluoroacetophenone (1.91 g) according to the method of description 36.

출처 및 근거

ORD 기록
ord-e6e0a3032d1c4193a10771658601bedb
출처 데이터셋
uspto-grants-2011_05
특허 번호
US07943645B2

연결된 노트

불러오는 중…