Boron tribromide → HCID 86614876, 화합물

HRID 549497노트

반응식

HRID 549497 반응식
B(Br)(Br)Br.[Br:5][C:6]1[CH:7]=[CH:8][C:9]2[CH:10]=[CH:11][C:12]3[C:17]([C:18]=2[CH:19]=1)=[CH:16][C:15]([O:20]C)=[CH:14][CH:13]=3>C(Cl)Cl>[Br:5][C:6]1[CH:19]=[C:18]2[C:9](=[CH:8][CH:7]=1)[CH:10]=[CH:11][C:12]1[CH:13]=[CH:14][C:15]([OH:20])=[CH:16][C:17]2=1

참가 물질

4

반응물 2

HCID 25134Boron tribromideHCID 866148773-Bromo-6-methoxyphenanthrene

생성물 1

HCID 86614876HCID 86614876, 화합물

시약·촉매·용매 1

HCID 6344Dichloromethane용매

실험 절차

To a flask containing BBr3 (1 M in CH2Cl2, 17 mL) at 0° C. was added a solution of 3-bromo-6-methoxyphenanthrene (1 g, 3.5 mmol) from Step 2, Example 160 in CH2Cl2 (10 mL). The reaction mixture was warmed to room temperature and stirred for 30 minutes, after which it was quenched with water. The aqueous layer was extracted with CH2Cl2. The organic layer was dried over MgSO4, filtered and concentrated to yield crude 6-bromophenanthren-3-ol.

후처리

  1. customafter which it was quenched with water
  2. extractionThe aqueous layer was extracted with CH2Cl2
  3. dry with materialThe organic layer was dried over MgSO4
  4. filtrationfiltered
  5. concentrationconcentrated

출처 및 근거

ORD 기록
ord-690a5db960b14dc89152afdfa76eafc3
출처 데이터셋
uspto-grants-2011_05
특허 번호
US07943649B2

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