3-Chloroaniline → 3-Phenylamino-pyrazine-2-carboxylic acid (3-chloro-phenyl)-amide

반응식

CO[C:3]([C:5]1[C:10]([NH:11][C:12]2[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=2)=[N:9][CH:8]=[CH:7][N:6]=1)=[O:4].[Cl:18][C:19]1[CH:20]=[C:21]([CH:23]=[CH:24][CH:25]=1)[NH2:22]>>[Cl:18][C:19]1[CH:20]=[C:21]([NH:22][C:3]([C:5]2[C:10]([NH:11][C:12]3[CH:17]=[CH:16][CH:15]=[CH:14][CH:13]=3)=[N:9][CH:8]=[CH:7][N:6]=2)=[O:4])[CH:23]=[CH:24][CH:25]=1

참가 물질

반응물 2

HCID 79323-Chloroaniline

HCID 13370930Methyl 3-anilinopyrazine-2-carboxylate

생성물 1

HCID 119966283-Phenylamino-pyrazine-2-carboxylic acid (3-chloro-phenyl)-amide

실험 절차

The title compound, MS: m/e=325.1 (M+H+), was prepared in accordance with the general method of example 1, step 2 from 3-phenylamino-pyrazine-2-carboxylic acid methyl ester and 3-chloroaniline.

출처 및 근거

ORD 기록: ord-58949919edbd4867adea46e2125e7a12
출처 데이터셋: uspto-grants-2011_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07947685B2

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