3-Fluoroaniline → 3-(3-Fluoro-phenylamino)-pyrazine-2-carboxylic acid (4-methyl-thiazol-2-yl)-amide

HRID 550582노트

반응식

HRID 550582 반응식
[CH3:1][C:2]1[N:3]=[C:4]([NH:7][C:8]([C:10]2[C:15](Br)=[N:14][CH:13]=[CH:12][N:11]=2)=[O:9])[S:5][CH:6]=1.[F:17][C:18]1[CH:19]=[C:20]([CH:22]=[CH:23][CH:24]=1)[NH2:21]>>[CH3:1][C:2]1[N:3]=[C:4]([NH:7][C:8]([C:10]2[C:15]([NH:21][C:20]3[CH:22]=[CH:23][CH:24]=[C:18]([F:17])[CH:19]=3)=[N:14][CH:13]=[CH:12][N:11]=2)=[O:9])[S:5][CH:6]=1

참가 물질

3

반응물 2

HCID 97423-FluoroanilineHCID 86607490HCID 86607490, 화합물

생성물 1

HCID 119963293-(3-Fluoro-phenylamino)-pyrazine-2-carboxylic acid (4-methyl-thiazol-2-yl)-amide

실험 절차

The title compound, MS: m/e=330.1 (M+H+), was prepared in accordance with the general method of example 4, step 2 from 3-bromo-pyrazine-2-carboxylic acid (4-methyl-thiazol-2-yl)-amide and 3-fluoroaniline.

출처 및 근거

ORD 기록
ord-632ebf8a9b75487eb16fa6a275f68ed5
출처 데이터셋
uspto-grants-2011_05
특허 번호
US07947685B2

반응 노트

불러오는 중…