Phosphorus oxide (P4O10) → 4-methyl-6H,7H-thieno[3,2-c]pyridine

HRID 550635노트

반응식

HRID 550635 반응식
F[C:2](F)(F)[C:3]([NH:5][CH2:6][CH2:7][C:8]1[S:9][CH:10]=[CH:11][CH:12]=1)=O.O=P12OP3(OP(OP(O3)(O1)=O)(=O)O2)=O>>[CH3:2][C:3]1[C:12]2[CH:11]=[CH:10][S:9][C:8]=2[CH2:7][CH2:6][N:5]=1

참가 물질

3

반응물 2

HCID 14812Phosphorus oxide (P4O10)HCID 571304842,2,2-trifluoro-N-[2-(thiophen-2-yl)ethyl]acetamide

생성물 1

HCID 218211774-methyl-6H,7H-thieno[3,2-c]pyridine수율 25%

실험 절차

In close analogy to the procedure described above, 2,2,2-Trifluoro-N-(2-thiophen-2-yl-ethyl)-acetamide is reacted with phosphorus pentoxide to provide the title compound.

출처 및 근거

ORD 기록
ord-79f00a2c64a744b78dbec112e3f81361
출처 데이터셋
uspto-grants-2011_05
특허 번호
US07947689B2

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