Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Imatinib → Imatinib Mesylate
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Imatinib | HCID 5291 | — |
| 반응물 | Methanesulfonic Acid | HCID 6395 | — |
| 생성물 | Imatinib Mesylate | HCID 123596 | — |
반응 단계
The solution in step-(a) may also be prepared by admixing imatinib base, methanesulfonic acid and the solvent medium to obtain a mixture; and heating the mixture to obtain a solution of imatinib mesylate. In one embodiment, the mixture is heated at a temperature of about 40° C. to about 110° C., and more preferably at about 50° C. to about 80° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US07947699B2 |
| 출처 데이터셋 | uspto-grants-2011_05 |
| ORD ID | ord-a4d6e77ffbd24d21a5a697e2ca41ae49 |
| 출처 메모 | uspto-grants-2011_05 |