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Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
HRID 550907생성일: 2026년 10월 26일

1-Fluoro-3-isocyanato-5-(trifluoromethyl)benzene → 3-{4-[3-(3-fluoro-5-trifluoromethylphenyl)-ureido]phenyl}-1H-pyrrolo[2,3-b]pyridine-2-carboxamide

https://huagongshe.com/reaction/550907

반응식

참여 물질

역할이름HCID투입량
반응물1-Fluoro-3-isocyanato-5-(trifluoromethyl)benzeneHCID 3445672—
반응물3-(4-aminophenyl)-1H-pyrrolo[2,3-b]pyridine-2-carboxamideHCID 57445354—
생성물3-{4-[3-(3-fluoro-5-trifluoromethylphenyl)-ureido]phenyl}-1H-pyrrolo[2,3-b]pyridine-2-carboxamideHCID 57445299—

반응 단계

78.1 mg of solid beige-coloured 3-{4-[3-(3-fluoro-5-trifluoromethylphenyl)-ureido]phenyl}-1H-pyrrolo[2,3-b]pyridine-2-carboxamide are prepared as described in Example 7 starting with 3-(4-aminophenyl)-1H-pyrrolo[2,3-b]-pyridine-2-carboxamide and 3-fluoro-5-trifluoromethylphenyl isocyanate.

출처 및 근거

DOI10.6084/m9.figshare.5104873.v1
특허 번호US07947706B2
출처 데이터셋uspto-grants-2011_05
ORD IDord-e5bf14c41b3c42fdb2f88a07c9111810
출처 메모uspto-grants-2011_05