Trifluoroacetic acid → (S)-1-(5-chloro-1H-benzimidazol-2-yl)-3-methoxypropylamine
반응식
C([NH:8][C@H:9]([C:14]1[NH:18][C:17]2[CH:19]=[CH:20][C:21]([Cl:23])=[CH:22][C:16]=2[N:15]=1)[CH2:10][CH2:11][O:12][CH3:13])(OC(C)(C)C)=O.C(O)(C(F)(F)F)=O>ClCCl>[Cl:23][C:21]1[CH:20]=[CH:19][C:17]2[NH:18][C:14]([C@@H:9]([NH2:8])[CH2:10][CH2:11][O:12][CH3:13])=[N:15][C:16]=2[CH:22]=1참가 물질
4
실험 절차
Prepared analogously to Example 1g from (1S)—N-Boc-1-(5-chloro-1H-benzimidazol-2-yl)-3-methoxy-propylamine and TFA in dichloromethane.
출처 및 근거
- ORD 기록
- ord-ba94615ce5184108849f489c1dfb3f74
- 출처 데이터셋
- uspto-grants-2011_05
- 특허 번호
- US07947700B2
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