Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Sodium hydride → 2-Chloro-4-methoxy-6-(3-thienylmethyloxy)pyridine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Sodium hydride | HCID 24758 | — |
| 반응물 | Thiophene-3-methanol | HCID 123570 | — |
| 반응물 | 2,6-Dichloro-4-methoxypyridine | HCID 3319993 | — |
| 용매 | Tetrahydrofuran | HCID 8028 | — |
| 생성물 | 2-Chloro-4-methoxy-6-(3-thienylmethyloxy)pyridine | HCID 19957398 | — |
반응 단계
To a solution containing 3-thiophenemethanol (0.45 g, 0.0033×1.2 mol) and sodium hydride (0.14 g, (ca.60% in mineral oil), 0.033×1.05 mol) in tetrahydrofuran, 2,6- dichloro-4-methoxypyridine (0.59 g, 0.0033 mol) was added and the resultant solution was refluxed for about 2 hours.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05624942 |
| 출처 데이터셋 | uspto-grants-1997_04 |
| ORD ID | ord-e3d7c7ceed4c4e008480e49f35bca82b |
| 출처 메모 | uspto-grants-1997_04 |