Toluene → HCID 86646155, 화합물

반응식

[CH2:1]([CH:4]1[CH2:8][CH2:7][O:6][CH:5]1[OH:9])[CH:2]=[CH2:3].[CH2:10]([O:12]C(P(C1C=CC=CC=1)(C1C=CC=CC=1)C1C=CC=CC=1)=O)C.[C:34]1([CH3:40])C=CC=C[CH:35]=1>>[OH:12][CH2:10][CH2:3][CH:2]([CH2:40][CH:34]=[CH2:35])/[CH:1]=[CH:4]/[C:5]([O:6][CH2:7][CH3:8])=[O:9]

참가 물질

반응물 3

HCID 1140Toluene

HCID 135457673-(Prop-2-en-1-yl)oxolan-2-ol

HCID 178473672HCID 178473672, 화합물

생성물 1

HCID 86646155HCID 86646155, 화합물

실험 절차

3-allyl-tetrahydrofuran-2-ol (18 g, 140 mmol) and ethoxycarbonyl triphenylphosphorane (35 g, 104 mmol) were stirred overnight in toluene (200 mL). The reaction solution was concentrated, and the residue was purified by silica gel column chromatography to obtain the compound of interest as an oil substance (15.8 g, 61.1%).

후처리

concentrationThe reaction solution was concentrated
customthe residue was purified by silica gel column chromatography
customto obtain the compound of interest as an oil substance (15.8 g, 61.1%)

출처 및 근거

ORD 기록: ord-27af5f9a4e42434abf0c6c363f642844
출처 데이터셋: uspto-grants-2011_05
DOI: 10.6084/m9.figshare.5104873.v1
특허 번호: US07947738B2

반응 노트

불러오는 중…