Ethyl chloroformate → 3beta-Carboethoxyandrost-5-ene-7,17-dione

HRID 551841

반응식

HRID 551841 반응식
[CH3:1][C@@:2]12[C:10](=[O:11])[CH2:9][CH2:8][C@H:7]1[C@@H:6]1[C:12]([CH:14]=[C:15]3[CH2:20][C@@H:19](O)[CH2:18][CH2:17][C@:16]3([CH3:22])[C@H:5]1[CH2:4][CH2:3]2)=[O:13].[CH2:23]([O:25][C:26](Cl)=[O:27])[CH3:24]>N1C=CC=CC=1>[C:26]([C@H:19]1[CH2:18][CH2:17][C@@:16]2([CH3:22])[C:15](=[CH:14][C:12](=[O:13])[C@@H:6]3[C@@H:5]2[CH2:4][CH2:3][C@@:2]2([CH3:1])[C@H:7]3[CH2:8][CH2:9][C:10]2=[O:11])[CH2:20]1)([O:25][CH2:23][CH3:24])=[O:27]

참가 물질

4

반응물 2

HCID 10928Ethyl chloroformateHCID 1933137-Keto-dehydroepiandrosterone

생성물 1

HCID 102370863beta-Carboethoxyandrost-5-ene-7,17-dione수율 90%

시약·촉매·용매 1

HCID 1049Pyridine용매

실험 절차

Prepared from (2) and ethylchloroformate in pyridine at 0-5° C. Yield 90%, m.p. 187-8° C.

출처 및 근거

ORD 기록
ord-50e1245c27cc44c5baaf2447c135f5a9
출처 데이터셋
uspto-grants-2011_05
특허 번호
US07947846B2

연결된 노트

불러오는 중…