Huagongshe화공사 화학 정보 인쇄 보고서 · 연구 참고용
Hydrazinecarboxaldehyde → 5,6-Dihydro-4H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepine
참여 물질
| 역할 | 이름 | HCID | 투입량 |
|---|---|---|---|
| 반응물 | Hydrazinecarboxaldehyde | HCID 12229 | — |
| 반응물 | 1,3,4,5-tetrahydro-2H-1,5-benzodiazepine-2-thione | HCID 4381402 | — |
| 용매 | 1-Butanol | HCID 263 | — |
| 생성물 | 5,6-Dihydro-4H-[1,2,4]triazolo[4,3-a][1,5]benzodiazepine | HCID 21837004 | 37.3% |
반응 단계
A mixture of 2,3,4,5-tetrahydro-1H-1,5-benzodiazepin-2-thione (0.8 g) and 0.80 g of N-formylhydrazine in 8 ml of n-butanol is stirred and refluxed for 18 hours and the solvent removed under vacuum. Ice water is added to the residual solid and the mixture filtered to give 0.312 g of a gray solid, m.p. 162°-165° C.
출처 및 근거
| DOI | 10.6084/m9.figshare.5104873.v1 |
|---|---|
| 특허 번호 | US05624923 |
| 출처 데이터셋 | uspto-grants-1997_04 |
| ORD ID | ord-6f93be46c0324cff9df89dfbf93931b7 |
| 출처 메모 | uspto-grants-1997_04 |