Ethanol → Ethyl 1-aminocyclopentane-1-carboxylate--hydrogen chloride (1/1)

HRID 552058노트

반응식

HRID 552058 반응식
[NH2:1][C:2]1([C:7]([OH:9])=[O:8])[CH2:6][CH2:5][CH2:4][CH2:3]1.S(Cl)([Cl:12])=O.[CH2:14](O)[CH3:15]>>[ClH:12].[CH2:14]([O:8][C:7]([C:2]1([NH2:1])[CH2:6][CH2:5][CH2:4][CH2:3]1)=[O:9])[CH3:15]

참가 물질

4

반응물 3

HCID 702EthanolHCID 2901CycloleucineHCID 24386Thionyl Chloride

생성물 1

HCID 3028134Ethyl 1-aminocyclopentane-1-carboxylate--hydrogen chloride (1/1)수율 93%

실험 절차

This was synthesised according to Standard Procedure 1, using 1-amino-1-cyclopentanecarboxylic acid (5.0 g, 38.6 mmol) with thionyl chloride (5.72 mL, 58 mmol) and anhydrous ethanol (29 mL). The product was isolated as a white solid (6.98 g, yield 93%).

후처리

  1. customThis was synthesised

출처 및 근거

ORD 기록
ord-abe7be6ca4e0492c86db4da8cdfbc3f6
출처 데이터셋
uspto-grants-2011_05
특허 번호
US07951787B2

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